ADVANCED MEDICAL INFORMATION AND EDUCATION (AMIE)
Product/ Object/Activity Increased/
Methlylation/arginine/specifically methylated by coactivator-associated arginine methyltransferase 1/CARM1/protein-arginine methyltransferase/previously shown to serve/transcriptional coactivator.
Product/ Object/Activity Diminished
mRNA degradation of cytokine/tnf/cytokines/
J. Biol. Chem/277/47/44623-44630
Hongwei Li/Sungmin Park/Britta Kilburn/Mary Anne Jelinek/Agnes Henschen-Edman/Dana W. Aswad/Michael R. Stallcup/Ite A. Laird-Offringa/02
activation of HuR hypoxia, lipopolysaccharide, and UV light. The mechanism by which these stimuli activate HuR is unclear and might be related to post-translational modification of this protein