Cytokines as anticancer treatments? Look at IL10 today and jalapenos

I assume that we can agree upon the tragedy of environmental toxins upon the
health of the world. Our diets make a difference as to the impact and exposure of these toxins. Vegetables, fruits that do not have pesticides can diminish the potential to these toxins such as oil by-products as well as other chemicals. Elimination of toxins from the food chain of the substance consumed can help also.

Nevertheless sometimes once one has been diagnosed with the dreaded initials MS, (multiple sclerosis) , SLE (systemic Lupus Erythematosis) or C word (Cancer), it is contingent upon him or her to eliminate the potential for their acceleration by continued exposure to toxins. The diminution of exposure diminishes potential of subsequent growth and toxicity of the cancer, MS or SLE or progression of the MS and the enhancement of response to treatments.

Some of this toxicity of the tumor is demonstrated through the production of the tumor of cytokines. Cytokines are of the inflammatory type produced by tumor cells and in general represent the Neanderthal but necessary Cro-Magnon but critical response to a foreign substance in normal White Blood Cells (lymphocytes) as allergic as opposed to antibody response. This is the Th1 response and yields the protein /hormone acting cytokines Interleukin 1, Interleukin 6 and Tumor Necrosis Factor (TNF) in normal lymphocytes under normal biochemical feedback inhibition

As in any protein production messenger RNA is templated if you will, to act as a pattern for each individual protein through Transfer RNA and nucleotide base assembly. Yet the critical length of time that the protein is produced necessary for its action is determined by the length of time the messenger RNA exits (its ½ life ). The substance HuR enhances the 1/2 life of the mRNA by attaching itself to the mRNA at the Uridine rich area. This throws the complete system of biochemical feedback inhibition off and there is an exaggerated production of things that become toxic.

The most toxic of these hormones is TNF because it is supposed to shrink tumors (tumor necrosis) but it turns on the collagenase/gelatinase MMP-9. The MMP-9 exposes more tissue if you will to requiring more TNF by penetrating neighboring basement membranes and hence a vicious cycle is created


What does all this mean? The HuR for the TNF and MMP-9 appear therefore to be the most likely candidate for cancer SLE, and MS treatment.
Keep your eyes pealed for natural and unconventional treatments that
effect this axis. IL10 appears to be a cytokine that may help in this endeavor.
Atorvastatin ( a statin drug lowering cholesterol ) increases IL10 and acts naturally to diminsh the inflammatory wing of the CYTOKINE CASCADE. So do jalapenos by blocking the receptor to Substance P which intiates the Inflammatory Cascade!

Dancers at the "ball" of MS, or 4th step

The continued separation of medicine is for politico-economic purposes only.
Without division there are greater possibilities for exchange of information.
This is particularly true for the kidney and the cardiovascular system. Due to their similar embryonic origin, studies involving glomerulonephritis invariably involve explanations of carditis. Since cardiologists do not seek after new treatments in the
nephrology field and vice versa there may be discoveries of sorts that are not being shared between the fields. There certainly has not been an economic stimulus to combine
departments at any medical schools that I know of. This would result in diminished
research funding and invasion of territory. There classically has been a competition
between the two fields and for one to be a cardiologist-nephrologist. Only a medical INFORMATICS department could have sway at collaborative studies in newly discovered information relative to cytokines and inflammatory causes of disease.

I realize this as I read articles form 2003 relative to the kidney that have similar pathologies in Multiple Scleorsis.

Here are the Players IL18, NK cells, HuR, MMP-9 ,TNF, IL1 cleaving

By studying one you solve the problem for 2. Lets block receptors of cytokines, prevent pro-enzyme activation, check our diet, drink water and figure this thing out. If your son had MS you would!


Nevertheless check this out

http://www.nature.com/ki/journal/v64/n1/full/4493856a.html

There is gold in them thar hills ( of nephrology), which will help us understand all disease.

You will love Advanced Medical Informatics Education (AMIE) and me too before it is all over, for the cures that it will bring your children and grandchildren! It may not be too late for your mental disease of evil. It is inflammatory and requires an antiinflammant treatment
( Anti Th1 )

Remember the all your fairy tales that your dad to told you? The stories?

If not we still love you but you need to read and act on the 4th step in 12/12 and do 1John 1:9 and repent while you have time, so you can begin to love yourself! PS do 1-3 then 5-12 thereafter

TNF

CURES FOR LEUKEMIA AND ALTZHEIMER'S

FOR THE BENEFIT OF ANYONE RICH AND POOR WHO HAS A RELATIVE WITH LEUKEMIA OR PRESENILE DEMENTIA...THERE IS HOPE ON THE WAY.

JUST AS AMIE PREDICTED OVER 12 YEARS AGO WITH ITS INFLAMMATORY PARADIGM FOR ALL DISEASES, THE AFOREMENTIONED DISEASES HAVE BEEN RELATED TO INFLAMATION AND ITS REGULATION THEREOF.

PLEASE SEE BELOW, IT IS VERY IMPORTANT.

Tumor Necrosis Factor

Too much of something can kill you. This was never as true for this "hormone" of sorts that is involved in the destruction of cells. The problem is once it is turned on, it is difficult to regulate if we are infected by something.

To make matters worst its counterpart TGF is involved in cancer.

Nevertheless it is imperative that I inform you of this ultimate killer that if in the nanomolar range becomes too concentrated, due to a lack of water to dilute it or poor circulation , can kill. This has been the classic problem involved in death of people from the time of Adam. It is involved with everything from LEPROSY TO LUPUS TO LUES TO THE LITTLE NAME DISEASE (AIDS) It is a grim reaper of sorts, yet necessary for tumor removal and dead cell removal.

It is under the Good Lord's control. It is out of control when we have the metabolic syndrome (high cholesterol, blood pressure and sugar). Cure = exercise, proper diet and water drinking in as many days as it took you to aquire the syndrome.

The medicine described below regulates the production of TNF and its "oxy" component is reported to work also in the production of red cells refractory to stimulation by a growth factor named erythorpoietin in Renal Failure.

Do not let this photo scare YOU. Everything is going down.