AMIE still functioning without data base open. There is Hope

BBC you are behind me in time that is to present the cause of how cancer spreads. We reported the collagenase MMP9 was responsible. This is a Zinc dependent collagenase that acts on a receptor whose activity is accelerated and diminished by various cytokines
http://alturl.com/htk . It was also stated as being responsible for Lupus, and MS
MMP9 was reported in our blog post over 60 days ago from old research (1991)to be the
cause of cancer growth and metastasis. There is nothing new under the sun. This certainly is not new but borrowed and flipped information. Actually to find a company to research this would the good to come out of it.The current cancer treatment methods including radiation and chemotherapy are afraid of losing market share and their political posistion in the Obama campain. Think about what new treatments could do to the pharm industry and their stocks. We post this information not to expect a massive stock sell-off but to give the poor, the noninsured hope.
You can not get into the cancer hospitals without 1. insurance that is good and 2. a diagnosis

Immunologic means of treatment as well as prevention should cure and prevent cancer deaths by as early as 5 years. The people will demand an end to unnecessasry cutting fying and poisoning especially if it is overpriced meanwhile .

So much for ignoring great men's advice. From the swine uncooked

http://tinyurl.com/dxk4p4

Streptococcus suis, an early colonizer of the upper respiratory tract, is a major swine pathogen worldwide that can cause meningitis, arthritis, pneumonia, and septicemia. While numerous studies on potential virulence factors of S. suis have been carried out over the past decade, the exact mechanisms by which this bacterium invades the host and migrates through the blood brain barrier (BBB) remain unclear. In the study presented here, we show that whole cells of S. suis were able to upregulate the production of prostaglandin E2 (PGE2) and matrix metalloproteinase 9 (MMP-9) by U937 human monoblastic cells differentiated into adherent macrophages in a dose- and time-dependent way. Capsular material and cell wall of S. suis were tested to determine which component was responsible for the induction of PGE2 and MMP-9 production by macrophages. The capsular material, even at low concentrations, strongly stimulated the production of PGE2 and MMP-9. While no stimulation was observed with the purified cell wall material, combining it with the capsular material resulted in a significant synergic effect on PGE2 and MMP-9 production. S. suis-mediated MMP-9 and PGE2 production by human macrophages may play a critical role in BBB disruption and tissue destruction.



Marie-Claude Jobina/Marcelo Gottschalk/Daniel Grenier/06

Comment:

The cell membrane component in recent research appears to be a Cluster of Differentiation receptor 44 . This appears to act as a docking station to allow for the MMP-9 to become "activated" Since in fact the MMP-9 component is to function as a syringe for metastasis of cancers, this membrane from this animal may be the nidus for the start of an autoimmune
granumatous formation that goes unnoticed until metastasis. That is my thought and I will sitck to it until I am proven wrong.

Cancer, MS LUPUS cures. Where are they?

see http://tinyurl.com/d6osnu

First of all MMP-9 as an enzyme has a normal function of remodeling the extracellular matrix. Without them as animal fat digestors the lack of remodeling probably would kill us by 22, and
we would die of heart attacks blind with renal failure. Talk about the metabolic syndrome! I wonder how much longer could we live sans exposure to animal fat.

Yu and Stamenkovicin 1999 were the first that I could find that associated the lack of inhibition of one of the most virulent cancer metastasis producers (MMP-9) to something outside of the molecule itself. In fact they surmised that the activity of the metaloproteinase was directly related to the physical restriction of an external cell receptor on the cell surface . It was they who surmised that the part of the iceburg that was necessary extended from the cell for the 'activation' if you will of the collagenase (MMP-9). This iceberg is a receptor for hyaluronan and docks the activated MMP-9 to do its thing. It is called CD44

We have discussed the role of HuR clinging in essential internal mRNA prolongation of 1/2 life. With these two substances so well researched 10 years ago you would think that the major cancer researchers especially in _____ would have cures related to them by now saving more lives. Yet they receive billions in federal kickback stimulation funds to continue restricting care to the indigent, especially the Black male. I call that indirect US paid genocide for hire. The legal profession is responsible for this as well as the legalized environmental racism which exposes poorer communities to known environmental toxins.

This will serve as the offical site of Advanced Medical Informatics Education. Our site is down
and we need to pay them. I will not be able to get a comparison to our old data but thank God we still have access to the net at least up until now. You can do the analytics now after I go on my forced no-internet sabatical on the 17th . There may be someone to take over the site. Let us hope so. Just compare MMP-9 to things that stop it and things that do not. There probable is a root in India , Africa or Brazil that can put it in check. Let us look for it.

Disease viewed as Intelligent?

Well again its Santa in late January. What I give you today is what I get. I
had assumed that a cell that is cancerous is intelligent. It was merely a guess that the
complexity of a cancerous cell’s metastasis or physiologic dysfunction such as the wasting syndrome or the disruption of the myelin sheath seen in Multiple Sclerosis,
with subsequent blurred vision, was a part of a grand theme. It was a conspiracy of sorts. It is one of the enemies' tools, namely to use self against the Spiritual Man.

It was not until I saw an article on Anthrax and its common ground of a LETHAL FACTOR in a metaloproteinase that I realized that I had hit pay dirt.. The field of microbiology is repleat with proof of this “intelligence”. Until we view the cancer as an intelligent “being “ of sorts we will lose the war on cancer. I will give you more as I get it.

This is why faith is important, because the wisdom of this "world" (its system, and tangible aspects) is foolishhness to God , the weak things of man are where God is strong and the unseen things are those things that will last and supercede the things seen in the empiric world. God has allowed the princes of the world to have their say and do their thing in order to allow for grace.

Have you read your Word today? Put on your whole armor and pray!

KPFT.org, Music Music Music and Medical Informatics

1.What are MMPs?
( formerly collagenases , have Zinc inside, Involved in atherosclerotic process, MS, Renal Disease. Turned on by TNF, IL1 and maintained by HuR. Turned off by TGF –beta, all of which are cytokines All this came from AMIE)


2.What is AMIE
(AN Invented software called Advanced Medical Informatics )
This allowed the development of the Cytokine Cycle and a way to prove its
existence from existing Index Medicus Data




3.How long have you been working on this cytokine cycle?
(since 1972 doing first
experiments with Peter and Professor Noteboom at the University of Missouri on RBCs receptors and Methadone, then with Professor Hirschburg at St. Louis University School of Medicine working on Gycoproteins and as their contribution to Cell Receptors.. I have had friends and patients die of MS and I was taught by any means necessary ( El Haj Malik). Nevertheless , I got distracted in Houston. Divorce/picking wrong mates, and people to assciate with. Not to say I am better. Due to identifying myself as hyperactive and trying to self treat it with Drugs and Alcohol . In ostracizing myself from my enemy ( no money) , the invention of AMIE has gained new life
Thank God for my sponsors including federal supervisors for the Federal Government. I took steps to stop and this is what got me back seriously on track. This is my story I am sticking to it but this is not about me. It is about an explanation of disease including psychiatric FROM ITS INFLAMMATORY PERSPECTIVE) IT IS POSSIBLE TO EXPLAIN EVIL AS AN ALLERGIC CONSEQUENCE OF SOMETHING INGESTED. I will be working with Dr. Sunshine on this as well as fasting as treatment in the future if God says the same

4. Discuss the Cytokine cycle and Th1 Th2 system as it articulates with MMP
(No different than Glycolytic, TCA, UREA cycles and respiratory chain There is a TH1,TH2 split so to speak It appears that unchecked TH1 cytokines called inflammatory IL1, TNF IL6 become unchecked and stimulate mRna of MMPs. IL1 recruits a stabilizing factor named HuR)

5. Why are MMPs important?

(PROTEAN MANIFESTATIONS- Nerve sheath ingestion of fast nerve axons-MS, Cancer Spread/basement membrane, atherosclerosis remodeling, arthritis, stokes, coagulation disorders, PEs)

6. Where do they work? Are there Good ones/bad ones?

(extracelular space, between cells on proteins to break them down. Yes as in the case of MMP 3,9 being involved in remodeling of atherosclerotic plaque)



7. What is the take home message?
An ounce of prevention
An ounce of prevention is worth a pound of cure. If you can not beat em do not lick em or you may catch something or get your a-- beat.

Christmas Present: Pathophysiology of TGF-beta /Explanation for Cancer and Autoimmune dis-Ease

The cure for some of the most enigmatic diseases centers around the pathophysiology of this hormone. In particular the understanding of granuloma pathophysiology and its association with cancer will unlock the key to pre metastatic disease recognition and treatment. Post metastatic disease will be best treated with anti-angiogenic mechanisms and conventional chemotherapeutic mechanisms for shorter periods.

Direct to tumor intraoperative therapies with intense allergenic stimuli (possibly sterilized RDs) associated with local corticosteroid therapy to the main tumor masses (liver/lung)
will lead to greater longevities and cures. This will reverse the nonfuctional tolerance associated with cancer metastasis. In addition intraoperative and impanted antineoplastins will lead to greater cures when followed up by better oral treatments. The availability of TNF-alpha free receptor will also ablate the general cathexis induced by TNF.

Stay tuned this data is hot off the press and I will follow for anyone especially the patients of North Medical Center the advancements that have been recognized by Advanced Medical Informatics Education. It will even be made available to Ray Taylor and all those who have played a part in shutting down the NORTH MEDICAL CENTER. by lying and not revealing evidence that would exonerate its doctor. I pray for them also.